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How GPX1 Variants Contribute to Cardiovascular Disease Hypertension: Increased ROS (reactive oxygen species) reduce nitric oxide (NO), impairing vasodilation
YAP Inhibition Restores Hepatocyte Differentiation in Advanced HCC, Leading to Tumor Regression
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In pathological states, this pathway may amplify pain inputs and promote visceral hypersensitivity (95)
[PubMed 27146802] 3505
In pre-clinical studies, it has been shown to exhibit neuroprotective effects in patients with ischemic brain injury
