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Multiple Cytochrome P450 Genes: their constitutive overexpression and permethrin induction in insecticide resistant mosquitoes culex quinquefasciatus

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However, this difference in flux was primarily due to nutrient composition differences between plasma and cell culture medium, with supraphysiological glucose concentrations and a lack of appropriate TCA cycle fuels (e.g., lactate, shared metabolic demand that prioritizes rapid biosynthesis over efficient energyketone bodies, amino acids) in the latter (10, 11)

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