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In addition to the chemical methods mentioned above, enzymes such as peroxygenase and other epoxy alcohol synthases/hydroperoxide isomerases can be used to generate hydroxy-epoxides from hydroperoxides

PloS one 12 , e0187724 (2017)

doi: 10.1016/j.nut.2006.08.013

doi: 10.3389/fcell.2020.603837 Received 08 September 2020 Accepted 30 November 2020 Published 12 January 2021 Volume 8 - 2020 Edited by Sergio Giannattasio, Consiglio Nazionale delle Ricerche, Istituto di Biomembrane, Bioenergetica e Biotecnologie Molecolari (IBIOM), Italy Reviewed by Cesare Indiveri, University of Calabria, Italy