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Description
Hydroxocobalamin is widely recommended for the treatment of diagnosed B12 deficiency, pernicious anaemia, fatigue related to low B12, and certain neurological symptoms associated with deficiency

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The change from uncompetitive to non-competitive mechanism induced by chemical modifications of the inhibitors is not rare in drug design studies 48,49,50

Meanwhile, the SSP modulates the mTOR/p70S6K and Wnt signaling pathways to accelerate cell cycle progression, exerting pro-proliferative effects in a variety of malignancies including melanoma and breast cancer

HSC70 recognizes cytosolic unfolded proteins containing KFERQ pentapeptide and delivers it to lysosomes by binding with the transmembrane receptor LAMP-2A [13, 14]

[DOI] [PMC free article] [PubMed] [Google Scholar] 220.Matos P., Collard J.G., Jordan P
