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Furthermore, the presence of certain biomarkers, such as ACAT2 expression, cholesteryl-ester burden, and SREBF2-activity signatures, may assist in the identification of patients who are most likely to benefit from these strategies, thereby serving as pharmacodynamic readouts during treatment

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Electrostatic forces are described by the function representing the expression for the Coulomb interaction: where is the permittivity, Q 1 and Q 2 are charges on the interacting atoms, and d is the interatomic distance

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