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Do not use normal saline, as salt can dissociate copper from the peptide

Clin Chem , 61(12), 14951504

GHK-Cu topical formulations are administered directly to the skin and massaged into the desired area
While essential for maintaining cerebral homeostasis, this barrier concurrently limits pharmacological interventions, often resulting in sub-therapeutic drug concentrations [140]
Because neither compound is licensed in the UK, no formal pharmacokinetic or pharmacodynamic interaction studies have been conducted or reviewed by the MHRA
