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The mechanism of LRT is multimodel in action, with lipid exerting both a scavenging effect (previously known as the lipid sink) and a direct cardiotonic effect

Busulfan with having two methanesulfonate groups, attached to two ends of a butane chain, hydrolyzes and releases extremely reactive positively charged carbonium ions, which react with the guanine molecules in cell's DNA, resulting in DNA interstrand crosslinks

Chen L, Qin Y, Liu B, Gao M, Li A, Li X, et al

However, there are major gaps in the existing literature that need to be addressed

Downstream targets of methyl CpG binding protein 2 and their abnormal expression in the frontal cortex of the human Rett syndrome brain