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A model of NAS docked into track B of the LPLA2 active site potentially explains the preference of the enzyme for lipophilic alcohols with a short side chain, such as C2 ceramide 29 , because this group would project towards the acyl-intermediate bound in track A (Fig
Therefore, potential drug development targeting the PRMT1-CEBPA pathway will probably provide new effective strategies for breast cancer treatment
Morgan Michael A
PubMedDirect Link Meleti, M., C
Journal of the Endocrine Society
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