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As SLEs immune dysregulation is so complex and with the very real possibility of herb-drug and supplement-drug interactions, PK/PD studies are imperative (233)

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After entering the thyroid follicle (or thyroid follicular cell) via a Na + /I symporter (NIS) on the basolateral side, iodide is shuttled across the apical membrane into the colloid via pendrin, after which thyroid peroxidase oxidizes iodide to atomic iodine (I) or iodinium (I + )

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Article last reviewed: April 05, 2026
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