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Teduglutide: Teduglutide is a GLP-2 analog with a glycine substitution at position 2 that confers DPP-4 resistance, extending half-life from 7 minutes to 2-3 hours

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The most commonly reported side effect in animal studies was mild local irritation at the injection site, which resolved without sequelae

These have been shown in models of muscle injury, tendon degeneration, and experimental colitis
However, higher doses increase cost without established evidence of proportionally increased benefit

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