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PubMed Central, Kivity, Shaye, et al

The structurally-related compound LVX was classified as a generally well tolerated non-DILI drug 20 associated with a substantially lower reporting rate of liver adverse effects compared to TVX 21

51 GaoT.McKennaB.LiC.ReichertM.NguyenJ.SinghT.et al (2014)
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Proof-of-concept therapeutic treatments, which overcome the impaired R152H GPX4 activity, including selenium supplementation, selective antioxidants and a deuterated polyunsaturated fatty acid were identified
