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Additionally, Res alleviated PM2.5-induced lung inflammation and fibrosis by inhibiting autophagy and NLRP3 inflammasome activity, reducing IL-1 in BEAS-2B cells ( 3.2.4 Terpenoids Triptolide, a bioactive diterpene from Tripterygium wilfordii , was shown to downregulate mRNA and protein expression of -SMA, type I collagen, FN, and vimentin, inhibiting lung fibroblast migration and transformation

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Grill, W

In the livers of patients with Wilson disease, as well as in corresponding animal models, both copper accumulation leading to cuproptosis and iron overload causing ferroptosis have been well documented
[DOI] [PMC free article] [PubMed] [Google Scholar] Voss S., Rademann J., Nitsche C
