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Each pathological state may damage the vascular endothelium of the CC through multiple potential mechanisms

Parsaeimehr A, Lutzu G

Patient-reported outcomes (PROs) and biomarker assessments in daNIS-3, a phase II platform study of NIS793 (antiTGF- monoclonal antibody) and other investigational drug combinations with standard of care (SOC) vs SOC alone in patients (pts) with second-line metastatic colorectal cancer (mCRC)
Rather than being an isolated cellular event, ferroptosis actively engages in a complex bidirectional crosstalk with the ocular immune system, driving neuroinflammation and tissue degeneration

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circ-Iqsec1 promoted osteogenesis of BM-MSCs via the miR-187-3p/Satb2 signaling pathway [170]