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Moreover, increased oxidative stress suppresses the expression of long-chain acyl-CoA synthetase-1, the key enzyme in fatty acid oxidation by mitochondria, ultimately leading to renal lipid accumulation in renal tubules and accelerating the development of obesity-related nephropathy [170,171]

This can make stomach-related symptoms more noticeable at first, especially in the early weeks or after a dose increase

RibeiroRMBrandMMaiaEJSantos-SilvaGOAbreuICNetoVFet alExtract and chloroform fraction from syzygium cumini leaves with vasorelaxant effect mediated by inhibition of calcium channels

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