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Description
Below outlines actionable strategies for achieving this vision (Figure 3): FIGURE 3 6.1 Precision risk stratification via genomics and microbiome profiling 6.1.1 Genomic biomarkers for radiation sensitivity Multi-gene panels for personalized risk assessment: Develop diagnostic panels incorporating radiation-responsive genes (e.g., ATM, TP53, XRCC1/2/3, NRF2) and single-nucleotide polymorphisms (SNPs) linked to DNA repair efficiency (e.g., XRCC1 399 Arg/Gln) and apoptosis regulation (e.g., P53 Pro/Arg72)

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