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10.1016/S0736-0266(03)00110-4 [DOI] [PubMed] [Google Scholar] Stupnisek M., Franjic S., Drmic D., Hrelec M., Kolenc D., Radic B., et al

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However, in the pivotal Phase IIb trial, it failed to demonstrate statistically significant weight loss compared to placebo at the primary endpoint, leading the developer (Metabolic Pharmaceuticals Ltd.) to terminate the commercial program