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NEJM Evid

This can be particularly beneficial for individuals with conditions like osteoarthritis, rheumatoid arthritis, tendonitis, or bursitis, where inflammation plays a central role in symptomatology

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Animal research using mice was conducted under a protocol approved by the UC Irvine Institutional Animal Care and Use Committee (IACUC) in compliance with the Animal Welfare Act and other federal statutes relating to animals and experiments using animals (Burke lab animal use protocol AUP-22-005 and AUP-25-004)

Moreover, experimental data show that the 5-methylTHFFR- complex is secreted by the choroid plexus as an exosome with several other proteins for uptake from the CSF by the brain parenchyma (80)

For each of the clusters, we identified highly enriched genes as putative novel markers of these PFG subpopulations (Supplementary Fig