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Mechanistic validation further confirmed downregulated expression of Nrf2, HO-1, and GPX4 in CLP mice, establishing a direct link between glutathione dysregulation and neuronal apoptosis

Pozefsky, T., Tancredi, R

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This study also shows that the gene differences between the MC58 pathogenic strain and the 522 carrier, in particular in the blood, may be caused by the activation of different sets of regulatory genes, in addition to RelA, including those encoding: i