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Additionally, OQ's oral median lethal dose (LD 50 ) was estimated to be higher than 2000 mg/kg, indicating its safety profile (Kale, Bambare, and Bhale 2023 )

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More importantly, it is necessary to use conditional gene knockout, overexpression models, and cross-validation with various OA models to distinguish the causal sequence, compensatory responses, and synergistic relationships between different molecules, laying the foundation for establishing truly precise and effective intervention strategies

MCF-7 cell lines (ATCC, USA) were cultured in RPMI 1640 media (EuroClone S.p.A., Italy) supplemented with 1% penicillin-streptomycin, 1% L-Glutamine, and 10% fetal bovine serum (FBS) and incubated in a 37 C incubator under 5% CO2 atmosphere

Mucins in the mucosal barrier to infection

doi:10.1161/jaha.123.029852