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This systematic review had two primary objectives: (1) To assess opioid peptide concentrations in individuals with ASD compared to typically developing controls (Table 1) (2) To evaluate the efficacy of GFCF dietary interventions on opioid peptide levels and ASD symptoms (Table 2)

Methylcobalamin should not be used in patients with early hereditary optic nerve atrophy (Lebers disease)

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