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5-HT is an important monoamine neurotransmitter in the central nervous system, and a decrease in its levels in the synaptic gap attenuates the activation of postsynaptic membrane 5-HT receptors (27), which destabilizes the neural loop of mood regulation and leads to psychiatric symptoms such as anxiety (26)

It has been studied for its potential benefits in neurodegenerative diseases like Alzheimer's

Souza-Silva EM, Alves RB, Simon KA, Hueza IM (2020) Crack cocaine smoke on pregnant rats: maternal evaluation and teratogenic effect

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