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In HT29 cancer cells, acidic intracellular conditions facilitated micelle disintegration, restoring fluorescence from ZnPc and Dox, and enabling 37.5 % and 50 % higher cell death with (PDT+Dox cytotoxicity) and without (Dox cytotoxicity only) light treatment compared to hydrazonefree controls

[DOI] [PubMed] [Google Scholar] Van Schooten FJ, Besaratinia A, De Flora S, DAgostini F, Izzotti A, Camoirano A, Balm AJ, Dallinga JW, Bast A, Haenen GR, Vant Veer L, Baas P, Sakai H, Van Zandwijk N

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Following treatment, 2,7-dichlorodihydrofluorescein diacetate (DCFH-DA) was added to a final concentration of 10 M and incubated at 37C for 30 min

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