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In 1990, Kodama et al

133 Maintenance of full GSH-Px and thioredoxin reductase activity by adequate dietary intake of selenium has been proposed to be useful in the prevention of several cardiovascular disorders

Since glutathione contains cysteine (a sulfur-containing amino acid), those with sulfur sensitivities might find that they feel slightly nauseous or experience skin flushing

Also involved in counteracting the effects of AGEs at the mitochondrial level

The damage equalizes the potential difference on both sides of the damaged membrane, preventing the formation of ATP
