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In contrast, 10 studies investigated the relationship between B12 supplementation status and homocysteine levels, encompassing a total of 191 participants (mean: 19.1 per study)

doi: 10.1016/0196-9781(94)90152-x

Long-term use should only continue under regular medical supervision

For example, some studies reported that pain relief lasted beyond the treatment session, while others did not find lasting nerve repair when nerve tissue was examined under a microscope

The American Medical Society for Sports Medicine (AMSSM) emphasizes the importance of quality control in regenerative medicine, noting that lack of precise control and biological characterization can impede clinical outcomes and pose safety risks

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