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Experimental evidence from in vitro and in vivo studies has demonstrated its inhibitory effects on the malignant progression of gliomas [16, 17]

A consistent model goes with ligation leading to vessel injury, exposure of tissue factors, stasis, thrombosis, hemodynamic changes, arterial hypotension, and in particular, venous hypertension, which approximates values over 20 mm Hg in the inferior caval vein, 101 thereby being roughly four times higher than those in normal rats

For the first three days I experienced extreme fatigue, and a very sore arm

When Auranofin and COJEC were administered on the same day, they were injected sequentially (COJEC first), allowing at least 2 h in between treatments to reduce animal discomfort

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