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Moreover, hyperglycaemia has been found to upregulate NADPH oxidase, whose primary role is to generate ROS [59]

In the study of RP, researchers have focused on the expression levels of genes involved in iron metabolism, as well as the levels of iron and oxidative damage within the retina

Interestingly, newborns with kernicterus have a higher chance of developing sensorineural hearing loss [30], suggesting a role of G6PD def in auditory disorders

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