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Synthesis, sensing, signaling, transport and physiological functions of proline have recently been reviewed (Hosseinifard et al

Preliminary efficacy results indicate that S-1226 may positively impact the management of cystic fibrosis-related lung disease

Numerous metabolites produced by cancer cells, including itaconate, L-kynurenine, lactic acid, and hyaluronic acid, have been demonstrated to activate Nrf2 and play a significant role in regulating the TIME and tumor-TAMs interaction

The enzyme beta-secretase cleaves APP to produce A peptides, particularly A42, which aggregate into toxic oligomers that form plaques

BMC Cancer (2016) 16(null):174

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