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Down-regulation of lung GSH content in hypoxia depends on peroxide tone of the cell and the p38(MAPK) system

Immunity 45 , 861876 (2016)

Importantly, alcohol consumption exacerbates the problem.[ref] Alcohol Metabolism Genotype Report Access this content: An active subscription is required to access this content

Researchers should expect attenuated rather than equivalent effects when extrapolating from preclinical data to human application

Researchers assumed that this was probably due to the sulphite formation in the nebulized solution and/or the metabolism of GSH into leukotrienes, potent pro-inflammatory bronchoconstrictors