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One approach, as mentioned above, is supplementing with NAD + precursors or analogues (Figure 3B)

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Additional mechanisms to avoid excessive accumulation of amino acids are metabolism and trans-inhibition of amino acid loaders, such as SNAT1/2 (ref

A completed trial sponsored by the University Hospital Tuebingen assessed the feasibility of using physical CAP for treating cervical intraepithelial neoplasia, with pathological remission after 36 months as the primary endpoint (NCT03218436)

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