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The study also revealed the underlying mechanism: autoantibodies and IFN- in SLE serum enhance the binding of the transcription suppressor CREM to the Gpx4 promoter, which in turn suppresses Gpx4 expression

The sequence read archive

Proc Natl Acad Sci USA 1990;87:40637

This inefficiency primarily stems from factors including poor nasal mucosal permeability of drugs, mucociliary clearance, short nasal residence time of drugs, and low bioavailability

It is recommended to explore more mechanisms of plant peptides to be more applicable in functional foods and dietetic supplements ( 6.3 Protection of muscle tissue The anti-fatigue recovers effect of plant-derived bioactive peptides on muscle have been widely focused (Table 2)

K., Macklin W
