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Indeed, the PDH complex, which decarboxylates glycolytically derived pyruvate to acetyl coenzyme A and links cytoplasmic glycolysis to the mitochondrial tricarboxylic acid (TCA) cycle, is modulated by reversible phosphorylation by PDH kinase (PDK)

Nicergoline showed a comprehensive positive effect on different levels of cerebral, systemic, and cardiac hemodynamics in ischemic stroke patients [71]

Dokmeci D, Inan M, Basaran UN, Yalcin O, Aydogdu N, Turan FN, et al

Interplay between cocaine, drug removal, and methylphenidate reversal on phospholipid alterations in Drosophila brain determined by imaging mass spectrometry

Subsequently, H 2 O 2 is further transformed into the highly reactive OH via the Fenton reaction, which requires the presence of reduced iron or copper ions (Halliwell and Gutteridge 1990)