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Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body

10.1016/j.androl.2020.01.009 55 OhkawaH.OhishiN.YagiK

[updated 2024 Mar 26

All in vivo experimental procedures were certified and approved by the Institutional Animal Care and Use Committee (IACUC) of Yonsei University Health System, which is certified by the Association for Assessment and Accreditation of Laboratory Animal Care International (AAALAC)

Once a drug products range of allowable denaturation has been identified, the next step in this process requires full denaturation of the protein solution as confirmed via physical separations of aggregates or characterization of tertiary or secondary structural changes

Ostrove, S