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Lenses collected for RNA extraction were placed in TRIzol Reagent (Invitrogen, Waltham, Massachusetts, USA) and then stored at -80C

M., Marini, V., Casiraghi, A

This inhibition renders GPX4 unable to perform its protective function due to shortage of its required co-substrate GSH, making chondrocytes more susceptible to ferroptosis

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135 Interestingly, studies have shown that HDL from CAD subjects activates protein kinase CII via LOX-1 leading to inhibition of eNOS activity via a mechanism involving reduced HDL PON1 activity and oxidative modification by endothelial cells
