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doi: 10.1007/s11104-008-9549-9

Pyruvate is oxidized and decarboxylated by the pyruvate dehydrogenase complex (PDC) in mitochondrial matrix to produce acetyl-CoA, as the beginning of the following tricarboxylic acid cycle (TCA cycle)
In: Lee PW, Aizawa H, Gan LL, Prakash C, Zhong D, editors

ZhaoZXFuJMaSRPengRYuJBCongLet alGut-brain axis metabolic pathway regulates antidepressant efficacy of albiflorin
indicated a significant negative correlation between total thiol (-SH) levels and headache duration in patients with MwoA (62)

So, the novel pH-sensitive nanocarrier can be applied to carrying and releasing DOX and calcium ions for cancer treatment (Asgari et al
