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Furthermore, multiple studies have demonstrated that collagen peptides can inhibit the expression of pro-inflammatory factors, such as tumor necrosis factor-alpha (TNF-), interleukin-1 beta (IL-1), IL-6, IL-8, inducible nitric oxide synthase (iNOS), and cyclooxygenase-2 (COX-2), in fibroblasts and keratinocytes, thereby mitigating inflammatory responses [32, 33]

It helps soften the look of fine lines, supports skin firmness and elasticity, and promotes a balanced, smooth skin texture for a revitalized appearance

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Epidemiological data linking higher IGF-1 levels within the normal range to modestly increased cancer incidence inform this caution

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The efficacy of the drug-loaded microspheres was evaluated at 4 and 8 weeks, and the bone-implant contact percentage was found to be significantly increased in the microspheres group