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Other agonists, such as the intestine-specific Fexaramine D (FexD), suppressed colitis-associated cancer (CAC) by restoring FXR signaling, enhancing intestinal barrier integrity, and reducing pro-inflammatory M1-like macrophage infiltration within the TIME (81)

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Control mice were treated with the same amount of DMSO after diluted in PBS

Number of cyto-c and cleaved caspase-9 positive cells increased after UVB irradiation compared to control (Non-UVB)

Lorillon P, Corbel JC, Mordelet MF et al

Research-grade Dihexa from suppliers like Real Peptides undergoes HPLC verification and mass spectrometry to confirm peptide sequence, purity (typically 98%), and absence of synthesis byproducts