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10.1016/j.envpol.2012.03.012 15 LeterrierM.ChakiM.AirakiM.ValderramaR.PalmaJ

Upon activation, microglia upregulate NADPH oxidase 2 which produces superoxide and inducible nitric oxide synthase, ultimately generating nitric oxide

Intra-articular injection of Cit-AuNRs@Anti-TRPV1 alleviates cartilage degradation by activating TRPV1 to inhibit ferroptosis in chondrocytes, reduces pain and improves physical activity in mice with medial meniscus instability-induced OA

10.1038/nrc.2016.138 130 ParkS

The ROS/GRK2/HIF-1/NLRP3 pathway mediates pyroptosis of fibroblast-like synoviocytes and the regulation of monomer derivatives of paeoniflorin

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