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A phase III clinical trial examining lapatinib, a dual EGFR/HER-2 tyrosine kinase inhibitor that inhibits the EGFR/HER-2 signaling pathway, has shown that lapatinib reverses resistance to trastuzumab in patients with breast cancer with trastuzumab resistance 86 ( Table 1 )
From reading the literature, I cant for the life of me tell whether this hypothesis is A) crazy, B) so obvious that everyone else already assumed it was true and hadnt bothered to say it out loud, or C) somewhere in between
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CD36 and ACAT-1 are connected with macrophage foam cell formation and aortic smooth muscle cell proliferation

In that regard, the 1 -AR Gly49 allele has been correlated with improved five-year survival (Tesson et al., 1999)

Although it is highly sensitive, silver staining has a very low dynamic range and tends to stain various other proteinaceous structures, making it a poor candidate for quantitative analysis
