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Two patients had pacemakers, one patient had pemphigus vulgaris, one had history of renal transplant, one had ulcerative colitis and one had tubercular arachnoiditis

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Inflammaging: a new immunemetabolic viewpoint for age- related diseases

Decreased secretion of Ltf leads to increased intracellular Fe concentration in neuronal cells, thereby exacerbating neuronal cell ferroptosis [123]

American Journal of Clinical Nutrition

The relatively low AUC of 0.64 for patient/carrier comparisons likely reflects overlap in age distribution, with many carriers already within the disease onset window, Supplemental Information Fig