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Several miRNAs showed increased expression in plasma, including miR-1555p, which normalised after treatment and could potentially serve as a marker for disease progression monitoring 114

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It is essential that the both the folate and methylation cycles are working optimally in order to satisfy daily methylation requirements

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This means they could affect the absorption of vitamin B12, which can potentially lead to vitamin B12 deficiency or worsen it in someone who already has it

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