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The above considerations suggest that two pharmacologically distinct mechanisms with opposite effects on the same signaling pathway are involved in a normally unresolvable physiological failure (complete obstruction (ligation) of vessels and ischemia due to a cause that could be not removed, inadequate rescue and unable to heal)

The process of regeneration is believed to occur either extrinsically by infiltration of external cells, intrinsically by tendon fibroblast proliferation, or both

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Information source: www.mdpi.com/journal/molecules

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Experimental and Therapeutic Medicine 15 (5), 44004408
