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et al., 2021), bacteriostatic (Wang et al., 2020), anti-viral (Tong et al., 2020), anti-inflammatory (Hu et al., 2021), immune regulation (Zhang M

Another study found that TMP via intracranial administration was able to prevent the cognitive behavioral phenotype of diabetes by modulating the SIRT1/Nrf2/HO-1 pathway, increasing the concentrations of GSH and SOD, as well as decreasing the content of mitochondrial DNA in the hippocampus of STZ-AD mice (119)

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In L4 spiny stellate neurons, Nlgn4-KO results in a significant decrease in the frequency of glutamatergic and GABAergic miniature currents (mEPSCs and mIPSCs)

In vitro, ibuprofen and other NSAIDs (naproxen, diclofenac, celecoxib) are not inhibitors of OAT4 at clinically relevant concentrations