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Lower levels of CRP reflect a reduction in systemic inflammation, which may mitigate endothelial dysfunction and slow atherosclerosis progression [64]

PMID: 11713213 3
doi: 10.1172/JCI14172

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The symptoms tend to get worse with age

Budnick I, Hamburg-Shields E, Chen D, Torre E, Jarrell A, Akhtar-Zaidi B et al