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The blockade of ERK1/2 activation by U0126 (a MAPK kinases inhibitor) attenuated the IRE1 level, suggesting that ERK1/2 activation causes ER stress activation in PFOS-treated RTCs (Fig

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Micale et al., 2017)

The most common type, mitral valve disease , occurs when the valve between the hearts chambers weakens and allows blood to leak backward