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By month 4, GI side effects fade into background noise for 85%+ of patients, leaving appetite suppression as the primary ongoing effect, which is the desired therapeutic response

Early detection and treatment can prevent severe clinical signs and improve quality of life

PM 10 or DEPs increase lung inflammation by inhaled allergens or respiratory viral infection by acting as adjuvants

Among the recruited cells, most monocytes differentiate into M2 macrophages (alternatively activated), which exhibit an anti-inflammatory phenotype

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Toxicol Ind Health 1995;11:423435