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Glutathiones protective and proactive properties help the skin renew itself, and allows the body to work optimally

Although HO-1 is commonly associated with cytoprotection and inhibition of cell death processes, excessive activation of HO-1 releases large amounts of Fe 2+ , leading to the accumulation of unstable iron pools and corresponding deleterious cyclic effects that exacerbate oxidative stress, presenting a dual effect that characterizes HO-1 as a double-edged sword

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17(2):155-61 (1998), which is hereby incorporated by reference))

10.1371/journal.ppat.1006928 155 Parodi-TaliceA.Monteiro-GoesV.ArrambideN.AvilaA