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This leads to the tempting speculation that there is also tiered system of AMP activity in the CNS, namely LTF and LL-37 acting as primary defense mechanisms, and once they become insufficient in their AMP activity, ApoE, A and Tau could then compensate for this insufficiency

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[DOI] [PMC free article] [PubMed] [Google Scholar] 204.Shakour N., Taheri E., Rajabian F., Tarighi S., Soheili V., Hadizadeh F