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Age-adjusted Charlson Comorbidity Index predicts survival in intrahepatic cholangiocarcinoma patients after curative resection

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Interestingly, a preclinical observation showed that ALC counteracted the loss of NMDA glutamate receptors in their neuronal membrane, as well as led to an increased production of neurotrophins, with the two effects relating to adaptive synaptic plasticity [72,92,93,94]