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4 Diabetes and high blood pressure are the leading causes of CKD, accounting for 75% of new cases in the United States
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As expected from our understanding of the function of hepatic ER, administration of a specific ER agonist (16-LE2 3 g/kg/day) alleviated hepatic steatosis in aromatase knockout mice (156)
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[DOI] [PubMed] [Google Scholar] 218.Kiefer D.S., Pantuso T
They have also consistently been shown to display excellent safety profiles, and a consideration of risks and benefits in their therapeutic potential should be placed within this context
