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Lukyanenko V, Gyorke I, Wiesner TF, Gyorke S

Metformin mitigates SASP secretion and LPS-triggered hyper-inflammation in doxorubicin-induced senescent endothelial cells

This is due to the fact that the effectiveness of other agents in other organs is also suggested due to their "cytoprotective" effects (e.g

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Site-directed mutagenesis experiments show that cysteine-553 in human GLCLC is involved in heterodimer formation between the catalytically active GLCLC and the auxiliary, activity-enhancing GLCLR unit, which likely occurs through a disulfide bond [139]

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